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Article

Antioxidants successfully reduce ROS production in propionic acidemia fibroblasts.

Biochemical and biophysical research communications - 26 Sept 2014

Gallego-Villar Lorena, Pérez Belén, Ugarte Magdalena, Desviat Lourdes R, Richard Eva

Abstract excerpt

Propionic acidemia (PA), caused by a deficiency of the mitochondrial biotin dependent enzyme propionyl-CoA carboxylase (PCC) is one of the most frequent organic acidurias in humans. Most PA patients present in the neonatal period with metabolic acidosis and hyperammonemia, developing different neurological symptoms, movement disorders and cardiac complications. There is strong evidence indicating that oxidative...

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Identifiers

PMID: 25159844
DOI: 10.1016/j.bbrc.2014.08.091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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