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Article

Somatic tumor testing implications for Lynch syndrome germline genetic testing.

Cancer genetics - 1 Jun 2022

Barrus Kathleen, Purington Natasha, Chun Nicolette, Ladabaum Uri, Ford James M

Abstract excerpt

Clinicians involved in cancer treatment often utilize somatic tumor sequencing to help tailor chemotherapy and immunotherapy. However, somatic tumor sequencing can also identify patients at risk for germline pathogenic variants causing cancer predisposition syndromes like Lynch syndrome. The extent to which clinicians realize this implication of tumor sequencing is currently unclear. We performed a retrospective...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35286930
DOI: 10.1016/j.cancergen.2022.02.010

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