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Tumor genome analysis includes germline genome: Are we ready for surprises?

6 Aug 2014

Abstract excerpt

We sought to describe the spectrum of potential and confirmed germline genomic events incidentally identified during routine medium-throughput somatic tumor DNA sequencing, and to provide a framework for pre- and post-test consent and counseling for patients and families. Targeted tumor-only next-generation sequencing (NGS) had been used to evaluate for possible druggable genomic events obtained from consecutive...

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PMID: 25123297
DOI: 10.1002/ijc.29128

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