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The relationship between polyunsaturated fatty acids and inflammation: evidence from cohort and Mendelian randomization analyses

2 May 2025

Abstract excerpt

BACKGROUND: Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) are thought to have anti- and pro-inflammatory roles, respectively, and influence the risk of various chronic diseases. However, it is unclear whether these associations are causal. METHODS: We examined the associations of dietary polyunsaturated FAs with biomarkers of systemic inflammation: C-reactive protein (CRP), glycoprotein...

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PMID: 40550517
DOI: 10.1093/ije/dyaf065

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