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Article

Piezo1 selectively enhances TGF-β1-induced IgA class switching by B cells

19 Jun 2025

Abstract excerpt

influx, gene transcription, and cell migration. Recent studies suggest that Piezo1 affects regulatory T cells differentiation and is critical in B cell responses to membrane-presented antigens. However, the role of Piezo1 in B cells function is not completely elucidated. This study investigated the role of Piezo1 in IgA class switching and Ab production by mouse B cells using qRT-PCR, flow cytometric analysis,...

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PMID: 40537609
DOI: 10.1007/s00018-025-05789-4

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