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Article

Targeting Piezo1 unleashes innate immunity against cancer and infectious disease

14 Aug 2020

Abstract excerpt

is regulated via up-regulation of histone deacetylase 2. Collectively, our work uncovers Piezo1 as a targetable immune checkpoint that drives immunosuppressive myelopoiesis in cancer and infectious disease.

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Identifiers

PMID: 32826342
DOI: 10.1126/sciimmunol.abb5168

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