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Single-cell spatial proteomics of non-relapse small cell lung cancer identifies tumor microenvironment determinants of survival

17 Jun 2025

Abstract excerpt

Small cell lung cancer (SCLC) is characterized by high malignancy and early propensity for metastasis, and modest response to immunotherapy due to the immunosuppressive microenvironment. Surgical intervention has shown benefits in treating early-stage SCLC. However, most patients experience recurrence after surgery. The factors associated with relapse free survival in these patients remain unclear. We collected...

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PMID: 40526293
DOI: 10.1007/s10565-025-10056-0

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