Article

Within-host competition sparks pathogen molecular evolution and perpetual microbiota dysbiosis

2024-09-03

Abstract excerpt

Pathogens newly invading a host must compete with resident microbiota. This within-host microbial warfare could lead to more severe disease outcomes or constrain the evolution of virulence. Using experimental evolution of a widespread pathogen ( Staphylococcus aureus ) and a native microbiota community in C. elegans nematode hosts, we show that a competitively superior pathogen displaced microbiota and reduced s...

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Literature Corpus work: 6c0d9011-890f-5e3f-948d-cc9ba31dc8dc
DOI: 10.1101/2024.09.03.610829

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