Article
Human pain genetics database: a resource dedicated to human pain genetics research.
Pain - 1 Apr 2018
Meloto Carolina B, Benavides Rodrigo, Lichtenwalter Ryan N, Wen Xia, Tugarinov Nicol, Zorina-Lichtenwalter Katerina, Chabot-Doré Anne-Julie, Piltonen Marjo H, Cattaneo Stefano, Verma Vivek, Klares Richard, Khoury Samar, Parisien Marc, Diatchenko Luda
Abstract excerpt
The Human Pain Genetics Database (HPGDB) is a comprehensive variant-focused inventory of genetic contributors to human pain. After curation, the HPGDB currently includes 294 studies reporting associations between 434 distinct genetic variants and various pain phenotypes. Variants were then submitted to a comprehensive analysis. First, they were validated in an independent high-powered replication cohort by...
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