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Dual Roles of Autophagy in Radiation‐Induced Brain Injury: Mechanistic Insights and Therapeutic Implications

1 Jun 2025

Abstract excerpt

BACKGROUND: Cranial radiotherapy, while essential for treating brain tumors, often leads to radiation-induced brain injury, a debilitating condition marked by cognitive decline and neuronal damage. Autophagy, a key cellular process for recycling damaged organelles and proteins, has emerged as both a protective and detrimental player in radiation-induced brain injury. METHODS: This review systematically explores...

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PMID: 40491058
DOI: 10.1111/cns.70464

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