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Article

Autophagy in brain tumors: a new target for therapeutic intervention.

Brain pathology (Zurich, Switzerland) - 1 Jan 2012

Kaza Niroop, Kohli Latika, Roth Kevin A

Abstract excerpt

The role of autophagy, traditionally considered a cellular homeostatic and recycling mechanism, has expanded dramatically to include an involvement in discrete stages of tumor initiation and development. Gliomas are the most aggressive and also the most common brain malignancies. Current treatment modalities have only a modest effect on patient outcomes. Resistance to apoptosis, a hallmark of most cancers, has...

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Identifiers

PMID: 22150924
DOI: 10.1111/j.1750-3639.2011.00544.x
PMCID: PMC3243074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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