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Mitophagy in Traumatic Brain Injury: A New Target for Therapeutic Intervention

1 Jan 2022

Abstract excerpt

Traumatic brain injury (TBI) contributes to death, and disability worldwide more than any other traumatic insult and damage to cellular components including mitochondria leads to the impairment of cellular functions and brain function. In neurons, mitophagy, autophagy-mediated degradation of damaged mitochondria, is a key process in cellular quality control including mitochondrial homeostasis and energy supply...

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PMID: 35126814
DOI: 10.1155/2022/4906434

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