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Article

Type 2 diabetes worsens the outcome of ischemia/reperfusion in female STEMI patients and female db/db mice with HFpEF cardiometabolic phenotype.

Cardiovascular diabetology - 7 Jun 2025

Iveljic Ivana, Young Megan, Corhodzic Elvira, Cullen Fenn, Prag Hiran A, Murphy Michael P, Aksentijevic Dunja

Abstract excerpt

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) poses a significant global health challenge, disproportionately affecting women. Diabetic women with HFpEF represent a high-risk subgroup, particularly after experiencing ST-segment elevation myocardial infarction (STEMI), exhibiting increased mortality compared to men. While prolonged door-to-balloon (DTB) times, reflecting delayed reperfusion,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40483445
DOI: 10.1186/s12933-025-02771-z
PMCID: PMC12144705

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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