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Article

Hereditary gingival fibromatosis: a case report with a novel SOS1 mutation and systematic review.

Oral surgery, oral medicine, oral pathology and oral radiology - 1 Oct 2025

Xie Yuhang, Liu Yixing, Sun Xiaomei, Wei Feng, Li Longjiang, Liu Zhe

Abstract excerpt

OBJECTIVES: Hereditary gingival fibromatosis (HGF) is a rare gingival disorder characterized by the slowly progressive, painless enlargement of the gums. This study aims to investigate a novel SOS1 mutation identified in a Chinese girl diagnosed with HGF. A comprehensive systematic review of the existing literature was conducted to enhance understanding of the clinical features and pathogenesis of HGF. STUDY...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40480946
DOI: 10.1016/j.oooo.2025.05.001

Genes

HGF
SOS1
MMP1
MMP13
MMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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Hereditary gingival fibromatosis: a case report with a novel SOS1 mutation and systematic review.PMID 40480946Read ↗

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