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Article

A novel gene ZNF862 causes hereditary gingival fibromatosis.

eLife - 10 Feb 2022

Wu Juan, Chen Dongna, Huang Hui, Luo Ning, Chen Huishuang, Zhao Junjie, Wang Yanyan, Zhao Tian, Huang Siyuan, Ren Yang, Zhai Teng, Sun Weibin, Li Houxuan, Li Wei

Abstract excerpt

Hereditary gingival fibromatosis (HGF) is the most common genetic form of gingival fibromatosis which is featured as a localized or generalized overgrowth of gingivae. Currently two genes (SOS1 and REST), as well as four loci (2p22.1, 2p23.3-p22.3, 5q13-q22, and 11p15), have been identified as associated with HGF in a dominant inheritance pattern. Here, we report 13 individuals with autosomal-dominant HGF from a...

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Identifiers

PMID: 35142290
DOI: 10.7554/eLife.66646
PMCID: PMC8856651

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