Article
Use of mutation profiles to refine the classification of endometrial carcinomas.
The Journal of pathology - 1 Sept 2012
McConechy Melissa K, Ding Jiarui, Cheang Maggie Cu, Wiegand Kimberly, Senz Janine, Tone Alicia, Yang Winnie, Prentice Leah, Tse Kane, Zeng Thomas, McDonald Helen, Schmidt Amy P, Mutch David G, McAlpine Jessica N, Hirst Martin, Shah Sohrab P, Lee Cheng-Han, Goodfellow Paul J, Gilks C Blake, Huntsman David G
Abstract excerpt
The classification of endometrial carcinomas is based on pathological assessment of tumour cell type; the different cell types (endometrioid, serous, carcinosarcoma, mixed, undifferentiated, and clear cell) are associated with distinct molecular alterations. This current classification system for high-grade subtypes, in particular the distinction between high-grade endometrioid (EEC-3) and serous carcinomas...
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