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Glymphatic dysfunction as a biomarker for post-stroke cognitive impairment

3 Jun 2025

Abstract excerpt

Ischemic stroke impacts glymphatic function, but its role in prognosis remains unclear. This study evaluated glymphatic function in 146 participants, including non-stroke (healthy controls, n = 48; nonvascular cognitive impairment patients, n = 47) and ischemic stroke cohorts (n = 51). The bilateral diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index, choroid plexus (CP), and...

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PMID: 40461672
DOI: 10.1038/s41598-025-04054-9

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