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Article

Alterations in the DTI-ALPS index and choroid plexus volume as brain-immune interfacing indicators in neuropsychiatric lupus erythematosus with inflammatory phenotype.

Lupus science & medicine - 28 Jan 2026

Liu Huiyang, Li Huanhuan, Tian Bailing, Jiang Yueluan, Li Zhenxing, Sun Zhen, Xia Yuwei, Shi Feng, Yang Pingting, Fan Guoguang, Liu Hu

Abstract excerpt

OBJECTIVES: This study aims to compare the diffusion tensor image analysis along the perivascular space (DTI-ALPS) index, choroid plexus (CP) volume and perivascular space (PVS) volume across different subtypes of neuropsychiatric systemic lupus erythematosus (NPSLE) in order to gain a deeper understanding of brain-immune interfacing dysfunction and neuroinflammation in these patients. METHODS: A total of 157...

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Identifiers

PMID: 41605603
DOI: 10.1136/lupus-2025-001815
PMCID: PMC12853556

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