Back to search

Article

The acquisition of <i>rmpADC</i> can increase virulence of classical <i>Klebsiella pneumoniae</i> in the absence of other hypervirulence-associated genes

2025-09-21

Abstract excerpt

<h4>ABSTRACT</h4> Klebsiella pneumoniae is one of the most common causes of nosocomial infections, and the rise of drug-resistant K. pneumoniae strains is complicating treatment and contributing to a mounting global health crisis. K. pneumoniae has two pathotypes, classical (cKp) and hypervirulent (hvKp). CKp typically cause opportunistic infections in immunocompromised individuals in healthcare settings and of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9a89158a-7535-55a2-bbe1-fea056810517
DOI
10.1101/2025.09.20.677538
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The acquisition of <i>rmpADC</i> can increase virulence of classical <i>Klebsiella pneumoniae</i> in the absence of other hypervirulence-associated genesDOI 10.1101/2025.09.20.677538
Genomic and functional analysis of rmp locus variants in Klebsiella pneumoniae.Semantic proximity
Differentiation of hypervirulent and classical <i>Klebsiella pneumoniae</i> with acquired drug resistanceSemantic proximity
Co-occurrence of ST412 <i>Klebsiella pneumoniae</i> isolates with hypermucoviscous and no-mucoviscous phenotypes in a short-term hospitalized patientSemantic proximity
Hypermucoviscosity in Klebsiella pneumoniae: manifestation, regulation, and roles in pathogenesis.Semantic proximity
Getting hypervirulent Klebsiella pneumoniae on the radar screenSemantic proximity
In-host evolution of classic to convergent <i>Klebsiella pneumoniae</i> sequence type 147 isolates and impact of associated capsular changes on different morphotypesSemantic proximity
Genomic Analysis of Multidrug-Resistant Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae Strain Lacking the Hypermucoviscous Regulators (rmpA/rmpA2)Semantic proximity
Presence of hypervirulence-associated determinants in Klebsiella pneumoniae from hospitalised patients in GermanySemantic proximity
The small protein RmpD drives hypermucoviscosity in <i>Klebsiella pneumoniae</i>Semantic proximity
Emergence of Dual-Risk <i>Klebsiella pneumoniae</i> : Global Hotspots of Convergence Between Resistance and HypervirulenceSemantic proximity
Genomic surveillance for multidrug-resistant or hypervirulent <i>Klebsiella pneumoniae</i> among bloodstream isolates at a United States academic medical centerSemantic proximity
The intersection of capsule gene expression, hypermucoviscosity and hypervirulence in Klebsiella pneumoniae.Semantic proximity
Select a neighboring publication to make it the new centre.