Improving Global Access to Genomic Profiling in Rare Pediatric Cancers.

doi:10.1158/1078-0432.CCR-24-3910

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Improving Global Access to Genomic Profiling in Rare Pediatric Cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2025

Farouk Sait Sameer, O'Donohue Tara J, Bale Tejus, Bowman Anita, Hill Katherine, Stockfisch Emily, Giantini-Larsen Alexandra, Alano Tina, Rosenblum Marc, Benhamida Jamal, Dunkel Ira J, Berger Michael, Arcila Maria E, Ladanyi Marc, Ortiz Michael V, Glade Bender Julia, Miller Alexandra, Chakravarty Debyani, Cavender Kelly, Preiser Benjamin, Zhang Hongxin, Kung Andrew L, Solit David B, Karajannis Matthias A, Shukla Neerav

Abstract excerpt

PURPOSE: To address financial barriers that limit access to genomic profiling and precision medicine, philanthropy-supported clinical genomic testing was offered worldwide at no cost to patients with select rare cancers via the Make-an-IMPACT program. Herein, we report our findings in pediatric patients with solid or central nervous system tumors. EXPERIMENTAL DESIGN: Tumor DNA or cerebrospinal fluid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Central Nervous System Neoplasms

Share to Circulating Tumor DNA

Share to Genetic Testing

Share to Genomics

Share to Neoplasms

Share to Precision Medicine

Share to Rare Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 40392980
DOI: 10.1158/1078-0432.CCR-24-3910
PMCID: PMC12233128

Genes

IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Improving Global Access to Genomic Profiling in Rare Pediatric Cancers.PMID 40392980Read ↗

An institutional review of genomic sequencing in pediatric solid tumors.Semantic proximity Read ↗

Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical CareSemantic proximity Read ↗

Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center.Semantic proximity Read ↗

Integrating genomics into clinical pediatric oncology using the molecular tumor board at the Memorial Sloan Kettering Cancer CenterSemantic proximity Read ↗

Clinical utility of custom-designed NGS panel testing in pediatric tumorsSemantic proximity Read ↗

Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer.Semantic proximity Read ↗

Whole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers.Semantic proximity Read ↗

Importance of Comprehensive Molecular Profiling for Clinical Outcome in Children With Recurrent CancerSemantic proximity Read ↗

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.Semantic proximity Read ↗

OncoKids: A Comprehensive Next-Generation Sequencing Panel for Pediatric Malignancies.Semantic proximity Read ↗

Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With CancerSemantic proximity Read ↗

Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experienceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.