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Article

Association of STAT6 gene polymorphism with atopic asthma among Yemeni children in Sana'a city, Yemen.

BMC pediatrics - 15 May 2025

Abdulwahab Masood Haitham, Mohammed Othman Arwa, Nasr Addin Al-Sonboli Najla, Abdulnoor Ghlab Faiza, Mohammed Al-Haidary Naif, Al-Shaibani Muhanna M

Abstract excerpt

BACKGROUND: Asthma is the most common chronic illness in children and is characterized by airway hyperresponsiveness, increased production of mucus, and significant inflammation. The signal transducer and activator of transcription 6 (STAT6) is a crucial gene in immune response, specifically in atopic reactions. It plays a role in the IL-4 and IL-13 signaling pathways in asthma and allergies. OBJECTIVE: This...

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Identifiers

PMID: 40375219
DOI: 10.1186/s12887-025-05710-9
PMCID: PMC12080117

Genes

STAT6

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