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Streamlined Genetic Education and Cascade Testing in Men from Hereditary Breast Ovarian Cancer Families: A Randomized Trial.

Public health genomics - 1 Jan 2024

Grisham Christopher, Peshkin Beth N, Sorgen Lia, Isaacs Claudine, Ladd Mary Kathleen, Jacobs Aryana, Binion Savannah, Tynan Mara, Kuchinsky Emily, Friedman Susan, Taylor Kathryn L, Graves Kristi, O'Neill Suzanne, Kim David, Schwartz Marc D

Abstract excerpt

INTRODUCTION: When a pathogenic BRCA1 or BRCA2 mutation is identified in a family, cascade genetic testing of family members is recommended since the results may inform screening or treatment decisions in men and women. However, rates of cascade testing are low, and men are considerably less likely than women to pursue cascade testing. To facilitate cascade testing in men, we designed a Web-based genetic...

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Identifiers

PMID: 39173603
DOI: 10.1159/000540466
PMCID: PMC11407795

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