Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Barriers to completion of cascade genetic testing: how can we improve the uptake of testing for hereditary breast and ovarian cancer syndrome?

Familial cancer - 1 Apr 2023

Kahn Ryan Matthew, Ahsan Muhammad Danyal, Chapman-Davis Eloise, Holcomb Kevin, Nitecki Roni, Rauh-Hain Jose Alejandro, Fowlkes Rana Khan, Tubito Francesca, Pires Maira, Christos Paul J, Tkachuk Kaitlyn, Krinsky Hannah, Sharaf Ravi N, Offit Kenneth, Lipkin Steven, Frey Melissa K

Abstract excerpt

Cascade testing for familial cancer syndromes has historically been difficult to execute. As part of a facilitated cascade testing pathway, we evaluated barriers to completion of cascade testing. Our previously published study evaluated a facilitated cascade testing pathway whereby a genetics team facilitated at-risk relative (ARR) cascade testing through telephone genetic counseling and mailed saliva kit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Genetic Counseling

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to Hereditary Breast and Ovarian Cancer Syndrome

Share to Ovarian Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 36207653
DOI: 10.1007/s10689-022-00316-x
PMCID: PMC10947313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Barriers to completion of cascade genetic testing: how can we improve the uptake of testing for hereditary breast and ovarian cancer syndrome?PMID 36207653Read ↗

Cascade genetic testing for hereditary cancer syndromes: a review of barriers and breakthroughs.Semantic proximity Read ↗

Psychosocial barriers and facilitators for cascade genetic testing in hereditary breast and ovarian cancer: a scoping review.Semantic proximity Read ↗

Uptake of Cascade Genetic Testing for Hereditary Breast and Ovarian Cancer: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Improving our model of cascade testing for hereditary cancer risk by leveraging patient peer support: a concept reportSemantic proximity Read ↗

Cascade Testing for Hereditary Cancer Syndromes: Should We Move Toward Direct Relative Contact? A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Cascade Genetic Risk Education and Testing in Families With Hereditary Cancer Syndromes: A Pilot Study.Semantic proximity Read ↗

Challenges and opportunities for Lynch syndrome cascade testing in the United States.Semantic proximity Read ↗

ACOG Committee Opinion No. 727: Cascade Testing: Testing Women for Known Hereditary Genetic Mutations Associated With Cancer.Semantic proximity Read ↗

Factors affecting the implementation of cascade testing of patients with BRCA1 or BRCA2 pathogenic germline variants in Japan.Semantic proximity Read ↗

ACOG Committee Opinion No. 727 Summary: Cascade Testing: Testing Women For Known Hereditary Genetic Mutations Associated With Cancer.Semantic proximity Read ↗

Timely targeted testing for hereditary cancer syndromes - Importance of clinician-facilitated cascade testing in the first year post-diagnosis.Semantic proximity Read ↗

Delivery Of Cascade Screening For Hereditary Conditions: A Scoping Review Of The Literature.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.