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Highly Sensitive DNA Testing of Fusobacterium nucleatum in Colorectal Tumors

15 May 2025

Abstract excerpt

BACKGROUND: Fusobacterium nucleatum (Fn) has been associated with the risk of colorectal cancer, poor colorectal cancer survival, and tumor attributes. Accurate and sensitive detection of Fn in tumor tissue is critical for evaluating their role in colorectal cancer. METHODS: We developed a droplet digital PCR (ddPCR) assay for detecting Fn using the transcription termination/antitermination gene (nusG) normalized...

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PMID: 40372237
DOI: 10.1158/1055-9965.epi-24-1020

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