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Article

Polygenic Risk Scores in Dilated Cardiomyopathy: Towards the Future.

Current cardiology reports - 14 May 2025

Kramarenko Daria R, Jurgens Sean J, Pinto Yigal M, Bezzina Connie R, Amin Ahmad S

Abstract excerpt

PURPOSE OF REVIEW: Genome-wide association studies (GWASs) have recently shown that common genetic variations significantly affect the risk of developing dilated cardiomyopathy (DCM). This has enabled the development of polygenic scores (PGSs), which aim to aggregate the impact of multiple common genetic variants across the genome to provide an overall genetic risk score for disease manifestation and disease...

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Source

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Identifiers

PMID: 40369171
DOI: 10.1007/s11886-025-02239-2
PMCID: PMC12078399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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