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Identification of a Distal Enhancer That Regulates TGF ‐β–Induced SNAI1 Expression

13 May 2025

Abstract excerpt

Snail is a zinc finger transcription factor encoded by the SNAI1 gene and triggers a cellular process termed epithelial-mesenchymal transition (EMT) upon its increased expression and/or functional activation. Snail expression and activity are regulated by various extracellular stimuli, including cytokines and environmental factors. Transforming growth factor-β (TGF-β) is a Snail inducer that functions via...

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PMID: 40364580
DOI: 10.1111/cas.70091

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