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Radiation-Induced Meningiomas Have an Aggressive Clinical Course: Genetic Signature Is Limited to NF2 Alterations, and Epigenetic Signature Is H3K27me3 Loss

1 Jan 2025

Abstract excerpt

Background: While the clinical course of radiation-induced meningioma (RIM) is considered to be more aggressive than that of sporadic meningioma (SM), the genetic predisposition for RIM is not established well.The present study aimed to analyze the clinical and genetic characteristics of RIMs to increase understanding of the tumorigenesis and prognosis of RIMs.Methods: We investigated a database of 24 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40359980
DOI: 10.3346/jkms.2025.40.e62

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