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Article

Accelerated epigenetic ageing worsens survival and mediates environmental stressors in fibrotic interstitial lung disease

30 Jan 2025

Abstract excerpt

Background The role of epigenetic ageing in the environmental pathogenesis and prognosis of fibrotic interstitial lung disease (fILD) is unclear. We evaluated whether ambient particulate matter with diameter ≤2.5 μm (PM2.5) and neighbourhood disadvantage exposures are associated with accelerated epigenetic ageing, and whether epigenetic age is associated with adverse clinical outcomes in patients with fILD....

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PMID: 39884761
DOI: 10.1183/13993003.01618-2024

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