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Single-Cell RNA Sequencing Reveals the Immune Landscape of Granulomatous Mastitis

8 May 2025

Abstract excerpt

Granulomatous mastitis (GM) is a form of non-lactational breast inflammation that is closely associated with autoimmune processes, however its underlying pathogenesis remains elusive. In this study, we employed single-cell RNA sequencing (scRNA-seq) to conduct a comparative analysis of GM lesion tissues versus normal breast tissues, thereby unveiling the immune profile of GM tissues. Our investigation centered on...

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PMID: 40338490
DOI: 10.1007/s10753-025-02310-8

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