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Article

Spatial transcriptional landscape of human heart failure

8 Apr 2025

Abstract excerpt

BACKGROUND AND AIMS: Heart failure (HF) remains a significant clinical challenge due to its diverse aetiologies and complex pathophysiology. The molecular alterations specific to distinct cell types and histological patterns during HF progression are still poorly characterized. This study aimed to explore cell-type- and histology-specific gene expression profiles in cardiomyopathies. METHODS: Ninety tissue cores...

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PMID: 40335066
DOI: 10.1093/eurheartj/ehaf272

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