Article
HLA allele and haplotype frequencies of registered stem cell donors in Chile.
Frontiers in immunology - 1 Jan 2023
Solloch Ute V, Giani Anette S, Pattillo Garnham Maria Ignacia, Sauter Jürgen, Bernas Stefanie N, Lange Vinzenz, Barriga Francisco, Fernández-Viña Marcelo A, Schmidt Alexander H
Abstract excerpt
Patients in need of hematopoietic stem cell transplantation often rely on unrelated stem cell donors matched in certain human leukocyte antigen (HLA) genes. Donor search is complicated by the extensive allelic variability of the HLA system. Therefore, large registries of potential donors are maintained in many countries worldwide. Population-specific HLA characteristics determine the registry benefits for...
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