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Article

HLA Class I and II allelic diversity among Ecuadorian transplant candidates: A comprehensive retrospective analysis.

Molecular immunology - 1 Jun 2025

Velasteguí Erick, Castillo María Esther, Ortiz Felipe, Espín Sofía, Espinel Eduardo, Loyola Luis Alberto, Báez-Cevallos David, Kyriakidis Nikolaos C, Romero-Alvarez Daniel, Baroja Isabel, Bastidas-Caldes Carlos

Abstract excerpt

The Major Histocompatibility Complex (MHC) comprises over 220 genes encoding proteins that are vital for the functioning of the immune system. These genes are divided into three classes: HLA class I, II, and III. The polymorphism of MHC genes serves to enhance the immune response by increasing the diversity of antigen presentation. In Ecuador, a country with a diverse population comprising numerous ethnic groups,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40239304
DOI: 10.1016/j.molimm.2025.03.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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