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Article

Mutation burden of narrowband ultraviolet B phototherapy (NB-UVB) in human skin: relevance to NB-UVB lifetime exposures and skin cancer surveillance.

The British journal of dermatology - 18 Sept 2025

Fowler Joanna C, Sood Roshan K, Coltart George, Lai Chester, Nadarajah Noeline, Holloway John W, Rose-Zerilli Matthew J J, Diffey Brian, Jones Philip H, Healy Eugene

Abstract excerpt

BACKGROUND: Ultraviolet radiation (UVR) is used as treatment for psoriasis and other skin diseases, but UVR can induce DNA mutations that may lead to skin cancer development. While skin cancers have been documented in patients treated with phototherapy, a limited number of epidemiological studies have examined the incidence of skin cancer in people receiving narrowband ultraviolet B (NB-UVB) treatment....

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Identifiers

PMID: 40317189
DOI: 10.1093/bjd/ljaf173
PMCID: PMC12448954

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