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Article

Relationship of Choline Intake with Biomarkers of Liver Health by Genotype-A Cross-Sectional Analysis.

The Journal of nutrition - 1 Jun 2025

Wallace Taylor C, Cowan-Pyle Alexandra E, Klatt Kevin C, Bailey Regan L

Abstract excerpt

BACKGROUND: Controlled feeding studies demonstrate that genetic variation in the folate-mediated one-carbon and choline metabolism pathway influence risk of organ dysfunction from consuming choline-deficient (<50 mg/d) diets. Whether genotype influences the relationship between choline intake and biomarkers of liver function in the general population remains unknown. OBJECTIVES: This study aims to conduct an...

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PMID: 40306555
DOI: 10.1016/j.tjnut.2025.04.020

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