Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between proband characteristics and CDH1 cascade genetic testing uptake in at-risk relatives.

Journal of genetic counseling - 1 Jun 2025

Fasaye Grace-Ann, Calzone Kathleen, Travis Elise, Gallanis Amber F, Gamble Lauren, Davis Jeremy L

Abstract excerpt

Cascade genetic testing involves testing at-risk relatives for a gene variant identified in the family to tailor clinical management. The first person in a family identified with a pathogenic or likely pathogenic variant is the proband. We aimed to determine proband characteristics associated with cascade testing for the CDH1 gastric and breast cancer susceptibility gene. Cascade genetic testing proportions in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cadherins

Share to CDH1 gene

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 40305395
DOI: 10.1002/jgc4.70011
PMCID: PMC12046368

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between proband characteristics and CDH1 cascade genetic testing uptake in at-risk relatives.PMID 40305395Read ↗

Differences in Cascade Genetic Testing Among Families With Hereditary Cancer Risk.Semantic proximity Read ↗

Cascade genetic testing: an underutilized pathway to equitable cancer care?Semantic proximity Read ↗

Communication With Clinicians and Relatives About Cascade Genetic Testing in Cancer Patients With Germline Pathogenic Variants.Semantic proximity Read ↗

Aligning Policy to Promote Cascade Genetic Screening for Prevention and Early Diagnosis of Heritable DiseasesSemantic proximity Read ↗

Cascade Genetic Risk Education and Testing in Families With Hereditary Cancer Syndromes: A Pilot Study.Semantic proximity Read ↗

Cascade genetic testing for hereditary cancer syndromes: a review of barriers and breakthroughs.Semantic proximity Read ↗

Comparison of CDH1 Penetrance Estimates in Clinically Ascertained Families vs Families Ascertained for Multiple Gastric CancersSemantic proximity Read ↗

30 year experience of index case identification and outcomes of cascade testing in high-risk breast and colorectal cancer predisposition genes.Semantic proximity Read ↗

Uptake of Cascade Genetic Testing for Hereditary Breast and Ovarian Cancer: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromesSemantic proximity Read ↗

Timely targeted testing for hereditary cancer syndromes - Importance of clinician-facilitated cascade testing in the first year post-diagnosis.Semantic proximity Read ↗

Factors affecting the implementation of cascade testing of patients with BRCA1 or BRCA2 pathogenic germline variants in Japan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.