Article
Genome-wide association study identifies three new melanoma susceptibility loci.
Nature genetics - 9 Oct 2011
Barrett Jennifer H, Iles Mark M, Harland Mark, Taylor John C, Aitken Joanne F, Andresen Per Arne, Akslen Lars A, Armstrong Bruce K, Avril Marie-Francoise, Azizi Esther, Bakker Bert, Bergman Wilma, Bianchi-Scarrà Giovanna, Bressac-de Paillerets Brigitte, Calista Donato, Cannon-Albright Lisa A, Corda Eve, Cust Anne E, Dębniak Tadeusz, Duffy David, Dunning Alison M, Easton Douglas F, Friedman Eitan, Galan Pilar, Ghiorzo Paola, Giles Graham G, Hansson Johan, Hocevar Marko, Höiom Veronica, Hopper John L, Ingvar Christian, Janssen Bart, Jenkins Mark A, Jönsson Göran, Kefford Richard F, Landi Giorgio, Landi Maria Teresa, Lang Julie, Lubiński Jan, Mackie Rona, Malvehy Josep, Martin Nicholas G, Molven Anders, Montgomery Grant W, van Nieuwpoort Frans A, Novakovic Srdjan, Olsson Håkan, Pastorino Lorenza, Puig Susana, Puig-Butille Joan Anton, Randerson-Moor Juliette, Snowden Helen, Tuominen Rainer, Van Belle Patricia, van der Stoep Nienke, Whiteman David C, Zelenika Diana, Han Jiali, Fang Shenying, Lee Jeffrey E, Wei Qingyi, Lathrop G Mark, Gillanders Elizabeth M, Brown Kevin M, Goldstein Alisa M, Kanetsky Peter A, Mann Graham J, Macgregor Stuart, Elder David E, Amos Christopher I, Hayward Nicholas K, Gruis Nelleke A, Demenais Florence, Bishop Julia A Newton, Bishop D Timothy
Abstract excerpt
We report a genome-wide association study for melanoma that was conducted by the GenoMEL Consortium. Our discovery phase included 2,981 individuals with melanoma and 1,982 study-specific control individuals of European ancestry, as well as an additional 6,426 control subjects from French or British populations, all of whom were genotyped for 317,000 or 610,000 single-nucleotide polymorphisms (SNPs). Our analysis...
Topics
- Case-Control Studies