Article
Evolution of carbapenemase activity in the class C β-lactamase ADC-1
28 Apr 2025
Abstract excerpt
ABSTRACT Antibiotic resistance in bacteria poses a significant threat to public health. Among dozens of available antimicrobial agents, carbapenems are used as drugs of choice for the treatment of serious infections caused by pathogens resistant to other antibiotics. However, their usefulness has been severely compromised due to the emergence and wide spread of carbapenem-resistant clinical isolates worldwide....
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