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Article

Molecular diversity of extended-spectrum β-lactamases and carbapenemases, and antimicrobial resistance

28 Jan 2020

Abstract excerpt

Along with the recent spread of multidrug-resistant bacteria, outbreaks of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing bacteria present a serious challenge to clinicians. β-lactam antibiotics are the most frequently used antibacterial agents and ESBLs, and carbapenemases confer resistance not only to carbapenem antibiotics but also to penicillin and cephem antibiotics. The mechanism of...

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PMID: 32015881
DOI: 10.1186/s40560-020-0429-6

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