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Article

Sex- and ALDH2-dependent differences in alcohol metabolism and psychomotor performance: a study in Han Chinese adults after binge drinking.

Annals of medicine - 1 Dec 2025

Ye Yi, Lin Yidie, Haseba Takeshi, Chen Fan, Cui Fanlai, Yi Xiaoqin, Fan Weihao, Li Gangqin

Abstract excerpt

BACKGROUND: Psychomotor impairments due to alcohol consumption may lead to a series of negative consequences. However, the influence of sex and ALDH2 polymorphism on psychomotor dysfunction has not yet been investigated. METHODS: One-hundred and three participants, genotyped for ALDH2 rs671, were administered a dose of 1.0 g/kg of white spirits. The blood ethanol concentration (BEC) and acetaldehyde concentration...

Read the complete abstract on PubMed

Topics

Humans
Male
Aldehyde Dehydrogenase, Mitochondrial
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Psychomotor Performance

Adult

Acetaldehyde

Ethanol

Genotype

Sex Factors

Binge Drinking

Young Adult

China

Reaction Time

Psychomotor Disorders

Blood Alcohol Content

East Asian People

Source

Open in PubMed Open full text

Identifiers

PMID: 40289679
DOI: 10.1080/07853890.2025.2496798
PMCID: PMC12039403

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

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