Article
Endosomal protein sorting and autophagy genes contribute to the regulation of yeast life span.
Autophagy - 1 Nov 2010
Longo Valter D, Nislow Corey, Fabrizio Paola
Abstract excerpt
Accumulating evidence from various organisms points to a role for autophagy in the regulation of life span. By performing a genome-wide screen to identify novel life span determinants in Saccharomyces cerevisiae, we have obtained further insights into the autophagy-related and -unrelated degradation processes that may be important for preventing cellular senescence. The generation of multivesicular bodies and...
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