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A Cytotoxic T Lymphocyte-Inspiring Microscale System for Cancer Immunotherapy

23 Apr 2025

Abstract excerpt

Adoptive T cell therapy (ACT) is an emerging cancer immunotherapy undergoing clinical evaluation, showing significant promise in the treatment of solid tumors. However, the clinical translation of ACT is hindered by its time-, labor-, and financial-consuming procedures, heterogeneity of cytotoxic T lymphocytes (CTLs), and immunosuppressive tumor microenvironment. Herein, we have developed a bionic cytotoxic T...

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PMID: 40268689
DOI: 10.1021/acsnano.4c19012

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