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Circular RNA‐Based Molecular Computation Enhances Plasma Biomarker Detection in Biliary Tract Cancer

21 Apr 2025

Abstract excerpt

Molecular diagnosis of biliary tract cancer (BTC) remains a significant clinical challenge due to the lack of sensitive and specific diagnostic tools. Although large panels based on multi-biomarkers have demonstrated potential in enhancing diagnostic accuracy, their clinical application is hindered by complexity and high costs. To overcome these limitations, we have developed a DNA-based molecular computation...

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PMID: 40259434
DOI: 10.1002/anie.202505289

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