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Article

Robust circulating microRNA signature for the diagnosis and early detection of pancreatobiliary cancer

21 Jan 2025

Abstract excerpt

BACKGROUND: A new circulating biomarker superior to carbohydrate antigen 19-9 (CA19-9) is needed for diagnosing pancreatobiliary cancer (PBca). The aim of this study was to identify serum microRNA (miRNA) signatures comprising reproducible and disease-related miRNAs. METHODS: This multicenter study involved patients with treatment-naïve PBca and healthy participants. The optimized serum processing conditions were...

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PMID: 39838364
DOI: 10.1186/s12916-025-03849-x

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