Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinicopathological and prognostic significance of DDX41 mutation in myeloid neoplasms: a systematic review and meta-analysis.

Annals of hematology - 1 May 2025

Miao Liying, Wang Xin, Yao Minghui, Tao Yihao, Han Yangyang

Abstract excerpt

DDX41 is one of the most frequently altered genes in familial acute myeloid leukemia/myelodysplastic syndrome (AML/MDS). Mutation of DDX41 has been widely reported in various types of myeloid neoplasms. This systematic review and meta-analysis were conducted to assess the clinical characteristics and relationship between DDX41 mutations and OS in myeloid neoplasm patients. We thoroughly searched the PubMed, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DEAD-box RNA Helicases
Share to DNA Methyltransferase 3A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNMT3A gene

Share to SRSF2 gene

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Myelodysplastic Syndromes

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 40257479
DOI: 10.1007/s00277-025-06278-1
PMCID: PMC12141167

Genes

DDX41
ASXL1
DNMT3A
SRSF2
TET2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinicopathological and prognostic significance of DDX41 mutation in myeloid neoplasms: a systematic review and meta-analysis.PMID 40257479Read ↗

Characteristics and clinical outcomes of patients with myeloid malignancies and DDX41 variants.Semantic proximity Read ↗

Genetic features and clinical outcomes of patients with isolated and comutatedDDX41-mutated myeloid neoplasmsSemantic proximity Read ↗

DDX41 mutations in myeloid neoplasms are associated with male gender, TP53 mutations and high‐risk diseaseSemantic proximity Read ↗

Germline DDX41 mutations define a significant entity within adult MDS/AML patientsSemantic proximity Read ↗

How to manage patients with germline DDX41 variants: Recommendations from the Nordic working group on germline predisposition for myeloid neoplasmsSemantic proximity Read ↗

Current Understanding of DDX41 Mutations in Myeloid NeoplasmsSemantic proximity Read ↗

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms.Semantic proximity Read ↗

Germline DDX41 Variants: Current Understanding and Future Directions.Semantic proximity Read ↗

The genetic landscape of germline DDX41 variants predisposing to myeloid neoplasms.Semantic proximity Read ↗

[DDX41-mutated myeloid neoplasms].Semantic proximity Read ↗

Myeloid neoplasms with germline DDX41 mutation.Semantic proximity Read ↗

Clinical and molecular correlates of somatic and germline DDX41 variants in patients and families with myeloid neoplasmsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.