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Genetic features and clinical outcomes of patients with isolated and comutatedDDX41-mutated myeloid neoplasms

18 Oct 2021

Abstract excerpt

DDX41 mutations (germline and somatic) are associated with late onset myelodysplastic syndromes/acute myeloid leukemia (MDS/AML). Myeloid neoplasms (MN) with germline predisposition was identified as a distinct category in the 2016 WHO classification revision, including MN with germline DDX41 mutation. We retrospectively analyzed the molecular findings and clinical characteristics of thirty-three DDX41-mutated...

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PMID: 34644397
DOI: 10.1182/bloodadvances.2021005738

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