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Article

Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.

PloS one - 1 Jan 2022

Goljan Ewa, Abouelhoda Mohammed, ElKalioby Mohamed M, Jabaan Amjad, Alghithi Nada, Meyer Brian F, Monies Dorota

Abstract excerpt

It is well documented that drug responses are related to Absorption, Distribution, Metabolism, and Excretion (ADME) characteristics of individual patients. Several studies have identified genetic variability in pharmacogenes, that are either directly responsible for or are associated with ADME, giving rise to individualized treatments. Our objective was to provide a comprehensive overview of pharmacogenetic...

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Identifiers

PMID: 35089958
DOI: 10.1371/journal.pone.0263137
PMCID: PMC8797234

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