Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary α-tryptasemia is Associated With Anaphylaxis to Antibiotics and Monoclonal Antibodies.

The journal of allergy and clinical immunology. In practice - 1 Jun 2025

Korošec Peter, Lyons Jonathan J, Svetina Manca, Koudová Monika, Bittóová Martina, Zidarn Mihaela, Sedláčková Lenka, Rijavec Matija, Kopač Peter

Abstract excerpt

BACKGROUND: Hereditary α-tryptasemia, a genetic trait caused by increased α-tryptase copy number, is associated with idiopathic and venom anaphylaxis. OBJECTIVE: We aimed to determine the impact of tryptase genotypes on drug-induced anaphylaxis. METHODS: A prospective discovery cohort of 99 patients from a referral center in Slovenia with acute anaphylaxis to drugs underwent tryptase genotyping by droplet digital...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaphylaxis
Share to Anti-Bacterial Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Monoclonal

Share to Drug Hypersensitivity

Share to Prevalence

Share to Slovenia

Share to Tryptases

Share to Young Adult

Source

Identifiers

PMID: 40239920
DOI: 10.1016/j.jaip.2025.04.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary α-tryptasemia is Associated With Anaphylaxis to Antibiotics and Monoclonal Antibodies.PMID 40239920Read ↗

Heritable risk for severe anaphylaxis associated with increased α-tryptase-encoding germline copy number at TPSAB1.Semantic proximity Read ↗

Hereditary Alpha-Tryptasemia: a Commonly Inherited Modifier of Anaphylaxis.Semantic proximity Read ↗

Hereditary Alpha-Tryptasemia: UK Prevalence and Variability in Disease Expression.Semantic proximity Read ↗

Incorporating Tryptase Genotyping Into the Workup and Diagnosis of Mast Cell Diseases and Reactions.Semantic proximity Read ↗

Hereditary Alpha-Tryptasemia and Mastocytosis: What We Know and What We Need To Learn.Semantic proximity Read ↗

Hereditary Alpha-Tryptasemia (HαT) as a Risk Modifier for Severe Anaphylaxis.Semantic proximity Read ↗

Hereditary alpha-tryptasemiaSemantic proximity Read ↗

Hereditary alpha-tryptasemia in 101 patients with mast cell activation–related symptomatology including anaphylaxisSemantic proximity Read ↗

Hereditary alpha tryptasemia is not associated with specific clinical phenotypes.Semantic proximity Read ↗

Clinically accessible amplitude-based multiplex ddPCR assay for tryptase genotyping.Semantic proximity Read ↗

Clinical impact of the TPSAB1 genotype in mast cell diseases: A REMA study in a cohort of 959 individuals.Semantic proximity Read ↗

High burden of clonal mast cell disorders and hereditary α-tryptasemia in patients who need Hymenoptera venom immunotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.