Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal relationship and mediation effects of immune cells and plasma metabolites in atopic dermatitis: A Mendelian randomization study.

Medicine - 11 Oct 2024

Yang Kaiwen, Zhong Jianqiao, Xian Dehai

Abstract excerpt

Atopic dermatitis (AD) is a chronic inflammatory skin condition with complex etiology involving genetic, environmental, and immunological factors. This study employs Mendelian randomization to explore the causal relationships between immune cell phenotypes and AD, and the mediating effects of plasma metabolites. Using data from European cohorts, we identified 7 immune cell phenotypes significantly associated with...

Topics

Join the communities discussing this publication.

Carnitine
Dermatitis, Atopic
GPI-Linked Proteins
Lipopolysaccharide Receptors
Mediation Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, CCR2

Source

Open in PubMed Open full text

Identifiers

PMID: 39465865
DOI: 10.1097/MD.0000000000039932
PMCID: PMC11479512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal relationship and mediation effects of immune cells and plasma metabolites in atopic dermatitis: A Mendelian randomization study.PMID 39465865Read ↗

The Causal Relationship Between Circulating Metabolites and the Risk of Atopic Dermatitis: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

The causal relationship between immune cells and atopic dermatitis: A bidirectional Mendelian randomization study.Semantic proximity Read ↗

Exploring causal correlations between circulating cytokines and atopic dermatitis: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

Mendelian randomization studies in atopic dermatitis: causal insights across omics layers.Semantic proximity Read ↗

Exploring the causal relationship between inflammatory cytokines and C-reactive protein levels and atopic dermatitis: a two-way two-sample Mendelian randomization studySemantic proximity Read ↗

Genetic Correlations and Causal Relationships Among Allergic Diseases: A Comprehensive Mendelian Randomization Study With Multiomic Mediation Analysis.Semantic proximity Read ↗

The causal relationship and potential mediators between plasma lipids and atopic dermatitis: a bidirectional two-sample, two-step mendelian randomization.Semantic proximity Read ↗

Mendelian Randomization Studies in Atopic Dermatitis: A Systematic Review.Semantic proximity Read ↗

Genetic support for the causal association between 91 circulating inflammatory proteins and atopic dermatitis: A two-sample Mendelian randomization trial.Semantic proximity Read ↗

Causal effects of circulating lipids and lipid-lowering drugs on the risk of atopic dermatitis: a mendelian randomization study.Semantic proximity Read ↗

Peripheral blood immune cell phenotypes and Alzheimer's disease: A mediation Mendelian randomization study.Semantic proximity Read ↗

Causal relationships between immunophenotypes, plasma metabolites, and temporomandibular disorders based on Mendelian randomization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.