Article
Genetic determinants and clinical significance of circulating and tumor-specific levels of insulin-like growth factor binding protein 7 (IGFBP7) in a Swedish breast cancer cohort.
Carcinogenesis - 3 Apr 2025
Godina Christopher, Rosendahl Ann H, Gonçalves de Oliveira Kelin, Khazaei Somayeh, Björner Sofie, Jirström Karin, Isaksson Karolin, Pollak Michael N, Jernström Helena
Abstract excerpt
Previous research indicates that insulin-like growth factor binding protein 7 (IGFBP7) protein levels in breast cancer tissue and blood are prognostic. However, genetic determinants of IGFBP7 in breast cancer remain largely unexplored. We examined IGFBP7 in a cohort of 1701 patients with first breast cancer from Sweden, enrolled prior to surgery 2002-16 and followed for up to 15 years. Genotyping was performed on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.