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Mendelian randomization study of IGF-1, childhood obesity and obesity-related asthma.

Cellular and molecular biology (Noisy-le-Grand, France) - 31 Oct 2023

Zhu Tianyi, Liu Hao, Ling Lan, Wang Yang, Jin Chao, Qi Jirong, Zhou Chen

Abstract excerpt

Insulin-like growth factor 1 (IGF-1) has been reported to potentially link with childhood obesity and obesity-related asthma, although a causal effect has not been illustrated. This study aimed to assess their association via multi-variable Mendelian randomization (MR) analysis with two-sample summary-level data on genetic variants as instrumental variables, thus estimating a causal effect. Genetic variants...

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PMID: 37953572
DOI: 10.14715/cmb/2023.69.10.22

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